欧宝综合

赵兴洪，教授，博士生导师，欧宝综合app引进“杰出人才”，兽医公共卫生安全全国重点实验室PI，ACS Infectious Diseases副主编。荷兰格罗宁根大学博士、博士后，师从荷兰皇家科ob欧宝电竞官网入口院士Oscar Paul Kuipers教授，入选2022年四川省“天府峨眉计划”青年科技人才项目。主要围绕Bacterial cell envelope-targeting antibiotics and delivery systems开展研究工作，包括基因组发掘、机器学习辅助肽类抗生素设计、生物合成、肽类分子理性改造、分子药理研究、抗生素精准递送系统构建等。研究成果以第一作者或通讯作者（含共同）身份在Nature Communications、Cell Chemical Biology、ACS Nano、Advanced Science、Advanced Materials、Journal of Controlled Release、BMC Biology、Antimicrobial Agents and Chemotherapy等专业领域权威杂志发表SCI收录论文30余篇。担任Nature Communications等权威杂志审稿专家。

欧宝综合app“杰出人才”科研启动经费，主持

[1] Xinghong Zhao^#,*, Xinyi Zhong^#, Shinong Yang^#, Jiarong Deng, Kai Deng, Zhengqun Huang, Yuanfeng Li, Zhongqiong Yin*, Yong Liu*, Jakob H. Viel, Hongping Wan*. "Guiding antibiotics towards their target using bacteriophage proteins." Nature Communications, 2024，15: 5287.

[2] Xinghong Zhao, Zhibo Li, and Oscar P. Kuipers*. "Mimicry of a Non-ribosomally Produced Antimicrobial, Brevicidine, by Ribosomal Synthesis and Post-translational Modification." Cell Chemical Biology, 2020, 27(10): 1262-1271.

[3] Hongping Wan#,*, Xinyi Zhong#, Shinong Yang#, Jiarong Deng#, Xu Song, Yong Liu*, Yuanfeng Li*, Zhongqiong Yin, Xinghong Zhao*. "Enhancing the Therapeutic Potential of Peptide Antibiotics Using Bacteriophage Mimicry Strategies." Advanced Science, 2025, 2411753.

[4] Xinghong Zhao^#,*, Jinhuan Liu^#, Xin Fan, Xinyi Zhong, Yijue Wang, Shinong Yang, Huirong Tan, Jiarong Deng, Xu Song, Shuyu Xie*, Renyong Jia*, Zhongqiong Yin, Hongping Wan*. “Cell wall binding proteins armed controlled-release nanodelivery system enhances nisin's efficacy against Streptococcus pneumoniae infections.” ACS Nano, 2025. (accept)

[5] Xiaowen Hu, Dongdong Li, Huaping Li, Yinzi Piao, Hongping Wan, Tieli Zhou, Mahdi Karimi, Xinghong Zhao*, Yuanfeng Li*, Linqi Shi, Yong Liu*. "Reaction-Induced Self-Assembly of Polymyxin Mitigates Cytotoxicity and Reverses Drug Resistance." Advanced Materials, 2024, 2406156.

[6] Xinghong Zhao, Zhongqiong Yin, Eefjan Breukink, Gert N. Moll, and Oscar P. Kuipers*. "An engineered double lipid II binding motifs-containing lantibiotic displays potent and selective antimicrobial activity against Enterococcus faecium." Antimicrobial Agents and Chemotherapy, 2020, 64(6), e02050-19. 

[7] Xiaojian Yan^#, Lei Hua^#, Hongping Wan^#, Yong Liu*, Tao Jin, Yicen Ge, Michael R Hamblin, Mahdi Karimi, Xinghong Zhao*, Yan Hu*, Linqi Shi, Yuanfeng Li*, “A Lipid with Lewis Pair-Mediated Targeting and Multiple Stimuli‐Responsive Delivery of Antibiotics for Bacterial Infections.” Advanced Science, 2025, e07407.

[8] Yongcheng He, Xu Song, Hongping Wan*, Xinghong Zhao*. " AmpHGT: expanding prediction of antimicrobial activity in peptides containing non-canonical amino acids using multi-view constrained heterogeneous graph transformer." BMC biology, 2025, 23: 184.

[9] Xinghong Zhao^#,*, Xinyi Zhong^#, Shinong Yang^#, Kai Deng, Lu Liu, Xu Song, Yuanfeng Zou, Lixia Li, Xun Zhou, Renyong Jia, Juchun Lin, Huaqiao Tang, Gang Ye, Jianqing Yang, Shan Zhao, Yifei Lang, Hongping Wan*, Zhongqiong Yin*, and Oscar P. Kuipers. "Elucidating the Mechanism of Action of the Gram-Negative-Pathogen-Selective Cyclic Antimicrobial Lipopeptide Brevicidine." Antimicrobial Agents and Chemotherapy, 2023, 67: e00010-23.

[10] Yumeng Wang^#, Xinghong Zhao^#, Xingjian Zhou^#, Juqin Dai, Xiaowen Hu, Yinzi Piao, Guangyue Zu, Jian Xiao*, Keqing Shi*, Yong Liu*, Yuanfeng Li*, Linqi Shi. "A supramolecular hydrogel dressing with antibacterial, immunoregulation, and pro-regeneration ability for biofilm-associated wound healing." Journal of Controlled Release, 2024, 368:740-755.