欧宝综合

从事畜禽养殖中环境因子与肠道健康之间的研究。相关研究成果以第一（含共同）在Journal of Pineal Research、Phytomedicine等国际权威杂志发表论文22篇，主持国家青年基金、北京市青年基金与北京市教改项目各一项，申请专利发明2项。曾获北京市优秀毕业生与北京市优秀博士学位论文，入选北京市2025年度青年人才托举工程。参与《猪解剖与组织学彩色图谱》与《犬猫解剖学彩色图谱》的编著与译注等工作。

2012年9月-2016年6月，福建农林大学，动物医学，学士

2016年9月-2021年6月，欧宝综合app，基础兽医学，博士

2021年8月-2023年8月，欧宝综合app，营养与健康系，博士后

2023年9月至今，欧宝综合app，欧宝综合体育基础兽医系，副教授

2021年：北京市优秀毕业生

2022年：北京市优秀博士学位论文

2025年：北京市青年人才托举

参讲《动物组织学与胚胎学》

1. 国家自然科学基金, 面上项目, 31873000, Wnt/β-catenin和NF-κB信号串扰在褪黑激素核受体介导单色光影响鸡淋巴细胞增殖中的作用, 2019-01-01 至 2022-12-31, 60万元, 资助期满, 参与； 

2. 欧宝综合app优秀人才项目，50万元，在研，主持；

3. 国家自然科学基金, 青年项目, 32402845, 丁酸调控巨噬细胞极化改善肉鸡应激性肠炎的机制研究，2025-01-01 至 2027-12-31, 30万元, 在研, 主持；

4. 北京自然科学基金，青年项目, 褪黑激素介导线粒体自噬调控脯氨酸生成改善皮肤衰老的分子机制，2024-01-01 至 2025-12-31, 20万元，在研，主持；

5. 北京市高等教育学会，面上课题，“双一流”建设背景下《动物组织学与胚胎学》课程教学改革探索，2025-2026，在研，主持。

1. Gao, T., Wang, Z., Dong, Y., Cao, J., Lin, R., Wang, X., Yu, Z., Chen, Y. Role of melatonin in sleep deprivation-induced intestinal barrier dysfunction in mice. J Pineal Res. 2019;67:e12574.

2. Gao, T., Wang, Z., Cao, J., Dong, Y., Chen, Y. Melatonin alleviates oxidative stress in sleep deprived mice: involvement of small intestinal mucosa injury. Int Immunopharmacol. 2020;78:106041.

3. Gao, T., Wang, Z., Cao, J., Dong, Y., Chen, Y. Melatonin attenuates microbiota dysbiosis of jejunum in short-term sleep deprived mice. J Microbiol. 2020;58:588-597.

4. Gao, T., Wang, Z., Cao, J., Dong, Y., Chen, Y. Melatonin ameliorates corticosterone-mediated oxidative stress induced colitis in sleep-deprived mice involving in gut microbiota. Oxid Med Cell Longev. 2021;2021:9981480.

5. Gao, T#., Wang, T#. Wang, Z., Cao, J., Dong, Y., Chen, Y. Melatonin-mediated MT2 attenuates colitis induced by dextran sodium sulfate via PI3K/AKT/Nrf2/SIRT1/RORα/NF-κB signaling pathways. Int Immunopharmacol. 2021;96:107779.

6. Gao, T., Wang, Z., Dong, Y., Cao, J., Chen, Y. Melatonin-mediated colonic microbiota metabolite butyrate prevents  acute sleep deprivation-induced colitis in mice. Int J Mol Sci. 2021;22:11894.

7. Gao, T., Wang, Z., Cao, J., Dong, Y., Chen, Y. The role of Aeromonas-goblet cell interactions in melatonin-mediated improvements in sleep deprivation-induced colitis. Oxid Med Cell Longev. 2022;2022:8133310.

8. Gao, T., Wang, Z., Cao, J., Chen, Y. Microbiota-gut-adipose axis: butyrate-mediated the improvement effect on inflammation response and fatty acid oxidation dysregulation attenuates obesity in sleep-restricted mice. Microbes Infect. 2023;9:105125.   

9. Gao, T., Wang, Z., Cao, J., Dong, Y., Chen, Y. Butyrate improved insufficient sleep-induced intestinal mucosal damage in human and mice. Microbiol Spectr. 2023;14;11:e0200022.

10. Gao, T., Li, Y., Wang, X., Tao, R., Ren, F. Bifidobacterium longum 68S mediated gut-skin axis homeostasis improved skin barrier damage in aging mice. Phytomedicine. 2023;120:155051.

11. Gao, T., Li, Y., Wang, X., Ren, F. Melatonin-mitochondrial axis: Engaging the repercussions of ultraviolet radiation photoaging on the skin’s circadian rhythm. Antioxidants. 2023;12:1000.

12. Gao, T., Li, Y., Wang, X., Ren, F. The role of probiotics in skin health and related gut-skin axis: A review. Nutrients. 2023;15:3123.

13. Gao, T., Li, Y., Wang, X., Ren, F. Alginate oligosaccharide-mediated butyrate-HIF-1α axis improves skin aging in mice. J Pharm Anal. 2024;14:100911.

14. Gao, T., Song, C., Wang, Z., Chen, Y. The vital role of melatonin in the intestinal mucosal barrier integrity in chick. Poult Sci. 2024;103(12):104487.

15. An, Y., Tan, S., Yang, J., Gao, T.*, Dong, Y*. The potential role of Hippo pathway regulates cellular metabolism via signaling crosstalk in disease-induced macrophage polarization. Front Immunol. 2024;14:1344697.

16. Quan, T., Li, R., Gao, T. Role of Mitochondrial dynamics in skin homeostasis: An update. Int J Mol Sci. 2025;26(5):1803.

17. Quan, T., Li, R., Gao, T. The intestinal macrophage-intestinal stem cell axis in inflammatory bowel diseases: From pathogenesis to therapy. Int J Mol Sci. 2025;26(7):2855.

18. Quan, T., Li, R., Gao, T. Molecular mechanism of melatonin-mediated mitophagy regulating proline production to ameliorate skin aging. Exp Gerontol. 2025;204:112738. 

19. Quan, T.; Zhang, W., Shi, Y., Gao, T. Melatonin-mediated intestinal microbiota homeostasis improves skin barrier damage involvement of gut-skin axis dysfunction in aging mice. Cell Signal. 2025;133:111859. 

20. Quan, T., Li, R., Chen, Y.X., Gao, T. Regulatory mechanism of intestinal stem cells based on Hippo pathway and signalling crosstalk in chicken. Int J Mol Sci. 2025;26:5067

21. Jiang, N.S., Quan, T., Li, R., Chen, Y.X., Gao, T. Role of nutritional elements in skin homeostasis: A review. Biomolecules. 2025;15:808.

22. 高婷#，王子旭，陈祝茗，曹静，董玉兰，董彦君，陈耀星. ROS介导的氧化应激与自噬[J]. 中国畜牧兽医. 2018;45:656-662.