欧宝综合

沈建忠，中国工程院院士，教育部人才项目特聘教授，国家杰出青年科学基金获得者，百千万工程领军人才（万人计划），现任兽医公共卫生安全全国重点实验室主任，第十四届全国政协委员。兼任教育部高等学校动物医学类专业教学指导委员会主任委员、国务院学位委员会第八届学科评议组召集人之一、联合国粮农组织（FAO）抗微生物药物耐药性参考实验室主任、One Health Advances杂志主编等。1980年考入北京农业大学，先后获得学士、硕士和博士学位。主要从事兽医公共卫生领域动物源性食品安全、微生物耐药性及新药创制等教学与科研工作。在Lancet Infectious Diseases、Nature Microbiology、PNAS等国内外重要学术期刊发表论文500余篇，主持承担973项目、国家重点研发计划、国家自然科学基金专项项目/重点项目等科研项目数十项，主持制定兽药残留检测方法国家和行业标准50余项。获国家自然科学二等奖、国家技术发明二等奖、国家科技进步二等奖等国家级奖励4项；获北京市自然科学一等奖、北京市科技一等奖等多项省部级奖励，先后培养硕士、博士研究生200余名。

1988年7月-1996年11月，北京农业大学兽医ob欧宝电竞官网入口/欧宝综合，助教/讲师

1996年12月-2001年11月，欧宝综合，副教授

2001年12月-至今，欧宝综合，教授

2004年4月-2012年3月，欧宝综合，副院长

2012年3月-2024年11月，欧宝综合，院长

1. 2023年度国家自然科学二等奖“可转移多黏菌素耐药基因mcr的发现及其传播机制研究”

2. 2020年度国家科学技术进步二等奖“食品动物新型专用药物的创制与应用”

3. 2015年度国家技术发明二等奖 “基于高性能生物识别材料的动物性产品中小分子化合物快速检测技术”

4. 2006年国家科学技术进步二等奖 “动物性食品中药物残留和化学污染物残留检测关键技术及试剂盒产业化”

5. 2019年度北京市自然科学一等奖 “可转移多黏菌素耐药基因mcr的发现及其传播机制研究”

6. 2005年北京市科学技术一等奖 “玉米赤霉醇和氯霉素等17种重要药物残留检测技术研究”

7. 2023年获北京市教育系统教书育人榜样

8. 2022年获全国杰出教学奖

9. 2020年获北京市先进工作者

10. 2020年获何梁何利基金科学与技术进步奖

11. 2018年获中华农业英才奖

12. 2017年获全国创新争先奖

13. 2010年获全国优秀科技工作者

14. 2004年获宝钢教育基金优秀教师奖

1. Xiaojia Liu, Meirong Song, Ying Liu, Shuyu Yang, Shang Chen, Jijun Kang, Jianzhong Shen*, Kui Zhu*, Rational Design of Natural Xanthones Against Gram-negative Bacteria, Advanced Science, 2025, 12(14):e2411923.

2. Leina Dou, Penghui Zhou, Fei Qi, Qing Li, Yuchen Bai, Liang Luo, Kai Wen, Wenbo Yu, Xuezhi Yu*, Jianzhong Shen*, Zhanhui Wang*. When AI meets AIE: machine learning in design function-oriented AIEgens for antibacterial ability. Chemical Engineering Journal, 2025, 524, 169426.

3. Tengfei Ma#, Ning Xie#, Yuan Gao, Jiani Fu, Chun E Tan, Qiu E Yang, Shaolin Wang, Zhangqi Shen, Quanjiang Ji, Julian Parkhill, Congming Wu, Yang Wang*, Timothy R Walsh*, Jianzhong Shen*. VirBR, a transcription regulator, promotes IncX3 plasmid transmission, and persistence of blaNDM-5 in zoonotic bacteria. Nature Communications, 2024, 15(1):5498.

4. Yingjie Zhang#, Jiafei Mi#, Weilin Wu, Jie Fei, Bochen Lv, Xuezhi Yu, Kai Wen, Jianzhong Shen*, Zhanhui Wang*. Investigation of antibody tolerance in methanol for analytical purposes: methanol effect patterns and molecular mechanisms. Advanced Science, 2024, 11, 2402050.

5. Shikai Song#, Shixin Yang#, Ruicheng Zheng#, Dandan Yin, Yue Cao, Yao Wang, Lu Qiao, Rina Bai, Shuge Wang, Wenjuan Yin, Yanjun Dong, Li Bai, Hui Yang, Jianzhong Shen*, Congming Wu*, Fupin Hu*, Yang Wang*. Adaptive evolution of carbapenem-resistant hypervirulent Klebsiella pneumoniae in the urinary tract of a single patient. Proc Natl Acad Sci U S A, 2024, 121(35):e2400446121.

6. Qian Li#, Shang Chen#, Kui Zhu*, Xiaoluo Huang, Yucheng Huang, Zhangqi Shen, Shuangyang Ding, Danxia Gu, Qiwen Yang, Hongli Sun, Fupin Hu, Hui Wang, Jiachang Cai, Bing Ma, Rong Zhang*, Jianzhong Shen*. Collateral sensitivity to pleuromutilins in vancomycin-resistant Enterococcus faecium. Nature Communications, 2022, 13(1):1888.

7. Dongyang Ye, Xiaowei Li, Jianzhong Shen, Xi Xia. Microbial metabolomics: From novel technologies to diversified applications. Trac-Trends in Analytical Chemistry, 2022, 148:116540.

8. Yang Wang#, Chunyan Xu#, Rong Zhang#, Yiqiang Chen#, Yingbo Shen#, Fupin Hu#, Dejun Liu, Jiayue Lu, Yan Guo, Xi Xia, Junyao Jiang, Xueyang Wang, Yulin Fu, Lu Yang, Jiayi Wang, Juan Li, Chang Cai, Dandan Yin, Jie Che, Run Fan, Yongqiang Wang, Yan Qing, Yi Li, Kang Liao, Hui Chen, Mingxiang Zou, Liang Liang, Jin Tang, Zhangqi Shen, Shaolin Wang, Xiaorong Yang, Congming Wu, Shixin Xu*, Timothy R Walsh*, Jianzhong Shen*. Changes in Colistin Resistance and mcr-1 Abundance in Escherichia coli of Animal and Human Origins Following the Ban of Colistin-Positive Additives in China: An Epidemiological Comparative Study. Lancet Infectious Disease, 2020, S1473-3099(20)30149-3.

9. Meirong Song#, Yuan Liu#, Xiaoyong Huang, Shuangyang Ding, Yang Wang, Jianzhong Shen*, Kui Zhu*, A Broad-Spectrum Antibiotic Adjuvant Reverses Multidrug-Resistant Gram-negative Pathogens, Nature Microbiology. 2020 Aug;5(8):1040-1050.

10. Tao He#, Ran Wang#, Dejun Liu#, Timothy R. Walsh, Rong Zhang, Yuan Lv, Yuebin Ke, Quanjiang Ji, Ruicheng Wei, Zhihai Liu, Yingbo Shen, Gang Wang, Lichang Sun, Lei Lei, Ziquan Lv, Yun Li, Maoda Pang, Liyuan Wang, Qiaoling Sun, Yulin Fu, Huangwei Song, Yuxin Hao, Zhangqi Shen, Shaolin Wang, Gongxiang Chen, Congming Wu, Jianzhong Shen*, Yang Wang*. Emergence of plasmid-mediated high-level tigecycline resistance genes in animals and humans. Nature Microbiology, 2019, 4(9):1450-1456.

11. Yingbo Shen#, Hongwei Zhou#, Jiao Xu, Yongqiang Wang, Qijing Zhang, Timothy R Walsh, Bing Shao, Congming Wu, Yanyan Hu, Lu Yang, Zhangqi Shen, Zuowei Wu, Qiaoling Sun, Yanran Ou, Yueling Wang, Shaolin Wang, Yongning Wu, Chang Cai, Juan Li, Jianzhong Shen*, Rong Zhang*, Yang Wang*. Anthropogenic and environmental factors associated with high incidence of mcr-1 carriage in humans across China. Nature Microbiology. 2018, 3(9), 1054-1062

12. Yang Wang#, Guobao Tian#, Rong Zhang#, Yingbo Shen#, Jonathan M. Tyrrell, Xi Huang, Hongwei Zhou, Lei Lei, Hongyu Li, Yohei Doi, Ying Fang, Hongwei Ren, Lanlan Zhong, Zhangqi Shen, Kunjiao Zeng, Shaolin Wang, Jian-Hua Liu, Congming Wu, Timothy R. Walsh*, Jianzhong Shen*. Prevalence, risk factors, outcomes, and molecular epidemiology of mcr-1-positive Enterobacteriaceae in patients and healthy adults from China: an epidemiological and clinical study. Lancet Infectious Diseases, 2017, 17(4), 390-399

13. Yang Wang#, Rongmin Zhang#, Jiyun Li, Zuowei Wu, Wenjuan Yin, Stefan Schwarz, Jonathan M. Tyrrell, Yongjun Zheng, Shaolin Wang, Zhangqi Shen, Zhihai Liu, Jianye Liu, Lei Lei, Mei Li, Qidi Zhang, Congming Wu, Qijing Zhang, Yongning Wu, Timothy R. Walsh*, Jianzhong Shen*. Comprehensive resistome analysis reveals the prevalence of NDM and MCR-1 in Chinese poultry production. Nature Microbiology, 2017, 2, 1-7

14. Yiyun Liu#, Yang Wang#, Timothy R Walsh, Lingxian Yi, Rong Zhang, James Spencer, Yohei Doi, Guobao Tian, Baolei Dong, Xianhui Huang, Linfeng Yu, Danxia Gu, Hongwei Ren, Xiaojie Chen, Luchao Lv, Dandan He, Hongwei Zhou, Zisen Liang, Jianhua Liu*, Jianzhong Shen*. Emergence of plasmid-mediated colistin resistance mechanism MCR-1 in animals and human beings in China: a microbiological and molecular biological study. Lancet Infectious Diseases. 2016, 16(2), 161-168.