欧宝综合

李浩，欧宝综合副教授，博士生导师，主要从事人畜共患病研究。主持国自然面上和中国博士后基金各1项，以项目骨干参与国自然3项和国家重点研发计划1项。以第一或通讯作者（含共同）在Nature Reviews Immunology，PNAS，Nature Communications，npj Vaccines等杂志发表相关文章30余篇。参编教材和专著2部，获8项国家发明专利授权。多次受邀参加国内外学术会议并作报告。担任Microbiology Spectrum杂志评审编辑, Frontiers in Immunology和JOVE杂志客座编辑，Infectious Medicine、Zoonoses、Science in One Health以及Biosafety and Health杂志青年编委。Science Translational Medicine、Vaccine、 Emerging Microbes & Infections、Molecular Immunology以及Tuberculosis等期刊特邀审稿人。

2004年9月-2008年7月，河南农业大学，专业为动物检疫，第二专业为法学，获理学学士和法学学士学位

2008年8月-2011年7月，军事医学科ob欧宝电竞官网入口，专业为微生物学，获理学硕士学位

2013年8月-2017年7月，清华大学，专业为生物学，获理学博士学位

2011年7月-2013年8月，清华大学医ob欧宝电竞官网入口，科研助理

2017年7月-2019年7月，清华大学医ob欧宝电竞官网入口，博士后研究员

1：人畜共患病结核病的疫苗开发及其引发的免疫保护机制研究。

2：分枝杆菌耐药机制研究。

3：微生物和宿主之间的相互作用。

2021 欧宝综合app教学成果二等奖

2024 欧宝综合app“人才培育发展支持计划”青年新星A

2026 2025 Extraordinary Service Award Microbiology Spectrum-ASM Journals

研究生课程：《兽医公共卫生专题》；

本科生课程：《兽医病理生理学》和《兽医病理生理学实验》等课程。

1. Jiahong Ji, Xiaoyi Jiang, Xinlei Liao, Fengjiao Du, Guirong Wang, Hairong Huang, Miao Mei, Yuan He, Xu Tan, Babak Javid#, Hao Li#. A monovalent SMAC mimetic as a potential host-directed therapy for tuberculosis. The Journal of Infectious Diseases, 2026. (#Corresponding author.)

2. Huoming Li, Hao Li#. Different antibody isotypes against tuberculosis: what we know and what we need to know. Frontiers in Immunology, 2025; 16:1682934. (#Corresponding author.)

3. Huoming Li, Jiahong Ji, Mengjin Qu, Xiuling Ma, You Zuo, Minghui Tang, Lingyuan Zeng, Hao Li#. Isolation and characterization of a protective monoclonal antibody targeting outer membrane protein (OmpA) against tuberculosis. Microbiology Spectrum, 2025: e0294224 (#Corresponding author.)

4. Lingyuan Zeng, You Zuo, Minghui Tang, Chengrui Lei, Huoming Li, Xiuling Ma, Jiahong Ji, Hao Li#. A subunit vaccine Ag85A-LpqH focusing on humoral immunity provides substantial protection against tuberculosis in mice. iScience, 2025, 111568. (#Corresponding author.)

5. Lingyuan Zeng, Hao Li#. Protocol for rapid evaluation of antibody-mediated protection in macrophages using immunofluorescence techniques. STAR Protocols, 2024, 5(4):103324. (#Corresponding author.)

6. Xiuling Ma, Huoming Li, Jiahong Ji, Lingyuan Zeng, Minghui Tang, Chengrui Lei, You Zuo, Hao Li#. Overexpression of Outer membrane protein A (OmpA) increases aminoglycoside sensitivity in Mycobacteria. BMC Microbiology, 2024, 24: 472. (#Corresponding author.)

7. Fengjiao Du, Yunyun Deng, Ling Deng, Boping Du, Aiying Xing, Hong Tao, Hua Li, Li Xie, Xinyong Zhang, Tao Sun#, Hao Li#. T-cell receptor and B-cell Receptor Repertoires Profiling in Pleural Tuberculosis. Frontiers in Immunology, 2024, 15. (#Corresponding author.)

8. Qing Sun, Xinlei Liao, Jun Yan, Guanglu Jiang, Fengmin Huo, Guirong Wang#, Hao Li#. In vitro activity of tubercidin against Mycobacterium tuberculosis and Nontuberculosis Mycobacteria. Journal of Medical Microbiology, 2023, 72(11). (#Corresponding author.)

9. Shivankari Krishnananthasivam*, Hao Li*, Rania Bouzeyen*, Bhuvaneshwari D/O Shunmuganathan, Kiren Purushotorman, Xinlei Liao, Fengjiao Du, Claudia Guldager Kring Friis, Felicity Crawshay-Williams, Heng Boon Low, Qian Xinlei, Conrad En Zuo Chan, Radoslaw Sobota, Mary Kozma, Valeria Barcelli, Guirong Wang, Hairong Huang, Andres Floto, Pablo Bifani, Babak Javid#, Paul A MacAry#. An anti-LpqH human monoclonal antibody from an asymptomatic individual mediates protection against Mycobacterium tuberculosis. npj Vaccines, (2023) 8:127. (*equal authorship.)

10. Mengjin Qu, Zhengmin Liang, Yulan Chen, Yuanzhi Wang, Haoran Wang, Ziyi Liu, Yiduo Liu, Yuhui Dong, Xin Ge, Hao Li#, Xiangmei Zhou#. Antibodies Targeting the Cell Wall Induce Protection against Virulent Mycobacterium bovis Infection. Microbiology Spectrum, 2023: e0343122. (#Corresponding author.)

11. Qing Sun, Xinlei Liao, Chenqian Wang, Guanglu Jiang, Jing Yang, Jianhong Zhao, Hairong Huang, Guirong Wang#, Hao Li#. In Vitro Activity of Fidaxomicin against Nontuberculosis Mycobacteria. Journal of Medical Microbiology, 2022, 71(6). (#Corresponding author.)

12. Mengjin Qu, Xiangmei Zhou#, Hao Li#. BCG vaccination strategies against tuberculosis: updates and perspectives. Human Vaccines & Immunotherapeutics, 2021:1-12. (#Corresponding author.)

13. Avia Watson*, Hao Li*, Bingting Ma*, Ronen Weiss, Danielle Bendayan, Lilach Abramovitz, Noam Ben-Shalom, Michael Mor, Erica Pinko, Michal Bar-Oz, Zhenqi Wang, Fengjiao Du, Yu Lu, Jan Rybniker, Rony Dahan, Hairong Huang, Daniel Barkan, Ye Xiang, Babak Javid, Natalia Freund. Human Antibodies Targeting a Transporter Mediate Protection Against Tuberculosis. Nature Communications, 2021, 12(1):602. (*equal authorship.)

14. 阮锦洋, 祁弋暄, 杜凤娇, 李浩#。结核分枝杆菌MPT83蛋白的表达纯化及其在免疫学诊断上的应用。中国热带医学，2023, 23(02)，115-120。

15. 唐明慧，李浩#。脂阿拉伯甘露聚糖的结构功能及其在结核病诊断中的应用。中国防痨杂志.，2022, 44(11)，1205-1212。