姓名：朱奎
性别：男
职称：教授
学位：博士
所在系：基础兽医系
导师类型：博导兼硕导
出生年月：1985.10
电子邮件：zhuk@cau.edu.cn
办公电话：010-62733695
个人简介
国家兽药安全评价（环境评估）实验室主任，兽医公共卫生安全全国重点实验室PI，美国杜克大学博士后、德国慕尼黑大学博士。主要围绕药物创制链，开展靶点发现与分子设计等研究，创制新药。主持国家自然科学基金青A（原杰青）、重点、国家重点研发计划等项目11项，以通讯作者在Cell、Nature Microbiology等期刊发表论文50余篇，为新药创制提供理论基础和技术支撑。
代表性文章
1, Han Y#, Liu X#, Qu S#, Duan X, Xiang Y, Jiang N, Yang S, Fang X, Xu L, Wen H, Yu Y, Huang S*, Huang J*, Zhu K*, Tissue geometry spatiotemporally drives bacterial infections, Cell, 2025, 188, 3459-3476.
2, Liu X#, Song M#, Liu Y, Yang S, Chen S, Kang J, Shen J*, Zhu K*, Rational design of natural xanthones against Gram-negative pathogens, Advanced Science, 2025, 2411923.
3, Chen X#, Song M#, Tian L#, Shan X, Mao C, Chen M, Zhao J, Sami A, Yin H, Ali U, Shi J, Li H, Zhang Y, Zhang J, Wang S, Shi C, Chen Y, Du X*, Zhu K*, Wu L*. A plant peptide with dual activity against multidrug-resistant bacterial and fungal pathogens, Science Advances, 2025, 11, eadt8239.
4, Chen S#, Liu D#, Wang L, Fan A, Xu N, Zhu K*, Lin W*, Marine-derived new peptaibols with antibacterial activities by targeting bacterial membrane phospholipids, Acta Pharmaceutica Sinica B, 2025, 15, 2764.
5, Li Q#, Feng H#, Tian Q, Xiang Y, Wang X*, He Y*, Zhu K*. Discovery of antibacterial diketones against Gram-positive bacteria, Cell Chemical Biology, 2024, 31, 1874-1884.
6, Song M#, Chen S#, Lin W, Zhu K*, Targeting bacterial phospholipids and their synthesis pathways for antibiotic discovery, Progress in Lipid Research, 2024, 96, 101307 (Invited)
7, Xu W, Yang G, Fang Y, Liu X, Ma X, Zhu K*. Coumarin glycosides reverse Enterococci-facilitated enteric infections, Research, 2024, 7, 0374.
8, Xu W#, Fang Y#, Shen J, Zhu K*. Enterococci facilitate polymicrobial infections, Trends in Microbiology, 2024, 32, 162-177. (Cover, Invited)
9, Huang Y#, Zhu Q#, Wang Y*, Zhu K*. Bacterial-derived sialidases inhibit porcine rotavirus OSU replication by interfering with the early steps of infection, Microbial Pathogenesis, 2024, 190, 106628.
10, Li X#, Qu S#, Song X, Wu C, Shen J*, Zhu K*. In situ neutralization and detoxification of LPS to attenuate hyperinflammation, Advanced Science, 2023, 2302950. (Cover)
