
姓名:张国中
性别:男
职称:教授
职务:副院长兼动物医学标本馆馆长
学位:博士
所在系:预防兽医系
导师类型:博导兼硕导
出生年月:1975.10
电子邮件:zhanggz@cau.edu.cn
办公电话:010-62733660
个人简介
副院长、二级教授、博士生导师,校畜禽疫病诊断研究中心主任、动物医学标本馆馆长。主要从事家禽传染病诊断与防控技术研究,目前承担国家重点研发计划、国家自然科学基金以及多项重大横向技术开发类研究项目。发表禽病相关学术论文100余篇,其中SCI收录论文80余篇;授权国家发明专利9项;获得省部级以上科研和教学奖励7项;获得新兽药证书2项,实现技术成果转化6项。担任教育部高等学校动物医学类专业教学指导委员会秘书长、中国兽医ob欧宝电竞官网入口院长联席会秘书长、中国兽医协会教育工作委员会秘书长、中国兽医协会专家委员会副主任委员、CNAS动植检专委会委员。
教育经历
2003.09-2006.07 博士,欧宝综合app,预防兽医学
1998.09-2001.07 硕士,欧宝综合app,预防兽医学
1994.09-1998.07 本科,欧宝综合app,兽医学专业
工作经历
2020.12-现在 教授,欧宝综合预防兽医学系
2012.12-2020.11 研究员,欧宝综合预防兽医学系
2006.12-2012.11 副研究员,欧宝综合预防兽医学系
2001.07-2006.11 助教、讲师,欧宝综合预防兽医学系
研究领域
重点聚焦传染性支气管炎病毒(IBV)、新城疫病毒(NDV)等家禽重要呼吸道病原,开展流行病学、感染与致病机理、传播与免疫机制以及新型疫苗创制等研究工作。
获奖及荣誉
2025 中国国际大学生创新大赛(2025)北京赛区三等奖(指导教师)
2024 中国畜牧兽医学会动物传染病学分会“突出贡献者”
2023 中国畜牧兽医学会禽病学分会“学术创新奖”
2023 中国技术市场协会第四届三农科技服务金桥奖一等奖(个人)
2023 第十届北京市大学生生物学竞赛三等奖(指导教师)
2022 北京市高等教育教学成果二等奖(2/12)
2021 入选教育部“国家高层次人才奖励计划”
2021 第七届中国国际“互联网+”大学生创新创业大赛优秀创新创业导师
2021 欧宝综合app教学成果奖特等奖(2/10)
2021 欧宝综合app优秀教师
2020 欧宝综合app校级代表性科研成果与重大社会服务贡献奖
2020 欧宝综合app研究生教育成果奖二等奖(1/6)
2019 欧宝综合app优秀共产党员
2018 中国学位与研究生教育学会研究生教育成果奖二等奖(4/5)
2018 欧宝综合app研究生教育成果奖特等奖(4/6)
2017 欧宝综合app优秀党务工作者
2015 山东省科技进步一等奖(3/12)
教学工作
2023-现在 主讲本科生课程《动物卫生经济学》
2019-现在 负责本科生课程《兽医专业概论》
2018-现在 负责博士生必修课《兽医科学进展》
2023-现在 参讲本科生课程《兽医社会学》
2017-现在 参讲动物科技ob欧宝电竞官网入口产业体系研究生课程《疫病防控》
2017-现在 参讲本科生课程《兽医科学进展与人类健康》
2013-现在 参讲研究生课程《畜禽疫病防治实践》
在研项目
1. “十四五”国家重点研发计划(课题):畜禽冠状病毒的感染与致病机理,2021-2024,主持人
2. “十四五”国家重点研发计划(任务):鸡传染性喉气管炎等亚单位疫苗创制,2022-2025,主持人
3. 国家自然科学基金-面上项目:Furin蛋白酶介导的S蛋白裂解在IBV引起急性肾损伤中的作用机制,2023-20226,主持人
4. 重大横向合作研究项目:禽用多联多价和新型疫苗的研制,2019-2023,主持人
5. 横向合作研究项目:新城疫、传染性支气管炎二联三价活疫苗的研制,2023-2028,主持人
代表性文章
1. Liang R, Tian J, Liu K, Ma L, Yang R, Sun L, Zhao J, Zhao Y*, Zhang G*. 2025. The cytoplasmic tail of IBV spike mediates intracellular retention via interaction with COPI-coated vesicles in retrograde trafficking. Journal of Virology 99(2):e0216424.
2. Huang M, Liukang C, Liang R, Li Y, Yang R, Zhang M, Zhao Y, Zhao J*, Zhang G*. 2025. Avian coronavirus IBV-induced activation of the NLRP3-Caspase-1-IL-1β axis in renal collecting ducts contributes to nephropathogenesis. Journal of Virology 99(12):e0146625.
3. Li Y, Duan L, Tang L, Huang M, Zhao Y, Zhang G*, Zhao J. 2025. Rapid reconstruction of infectious bronchitis virus expressing fluorescent protein from its nsp2 gene based on transformation-associated recombination platform. Journal of Virology 99(7):e0053525.
4. Liukang C, Zhao J, Tian J, Huang M, Liang R, Zhao Y, Zhang G*. 2024. Deciphering infected cell types, hub gene networks and cell-cell communication in infectious bronchitis virus via single-cell RNA sequencing. PLoS Pathogens 20(5):e1012232.
5. Chen X, Zhao J, Yue S, Li Z, Duan X, Lin Y, Yang Y, He J, Gao L, Pan Z, Yang X, Su X, Huang M, Li X, Zhao Y, Zhang X, Li Z, Hu L, Tang J, Hao Y, Tian Q, Wang Y, Xu L, Huang Q, Cao Y, Chen Y, Zhu B, Li Y*, Bai F*, Zhang G*, Ye L*. 2024. An oncolytic virus delivering tumor-irrelevant bystander T cell epitopes induces anti-tumor immunity and potentiates cancer immunotherapy. Nature Cancer 5(7):1063-1081.
6. Liang R, Liu K, Li Y, Zhang X, Duan L, Huang M, Sun L, Yuan F, Zhao J, Zhao Y*, Zhang G*. 2024. Adaptive truncation of the S gene in IBV during chicken embryo passaging plays a crucial role in its attenuation. PLoS Pathogens 2024 Jul 30;20(7):e1012415.
7. Zhao J, Huang Y, Liukang C, Yang R, Tang L, Sun L, Zhao Y, Zhang G*. 2024. Dissecting infectious bronchitis virus-induced host shutoff at the translation level. Journal of Virology 98(7):e0083024.
8. You R, Liu K, Huang M, Tang L, Zhang X, Huang Y, Zhao J, Zhao Y, Ye L, Zhang G*. 2023. Identification and comparison of the sialic acid-binding domain characteristics of avian coronavirus infectious bronchitis virus spike protein. Journal of Virology 97(5):e0048923.
9. Li X, Zhao Y, Teng QY, Zhang XH, Xue J, Zhang GZ*. 2023. Methyltransferase K-D-K-E motif influences the intercellular transmission of Newcastle disease virus. Virulence 14(1):2186336.
10. Zhao J, Feng DL, Zhao Y, Huang M, Zhang XH, Zhang GZ*. 2022. Role of stress granules in suppressing viral replication by the infectious bronchitis virus endoribonuclease. Journal of Virology 96(12):e0068622.
11. Qin YF, Teng QY, Feng D, Pei Y, Zhao Y, Zhang GZ*. 2022. Development of a nanoparticle multiepitope DNA vaccine against virulent infectious bronchitis virus challenge. Journal of Immunology 208(6):1396-1405.
12. Zhao J, Sun L, Zhao Y, Feng DL, Cheng JL, Zhang GZ*. 2021. Coronavirus endoribonuclease ensures efficient viral replication and prevents protein kinase R activation. Journal of Virology 95(7): e02103-20.
13. Yang YL, Xue J, Teng QY, Li X, Bu YW, Zhang GZ*. 2021. Mechanisms and consequences of Newcastle disease virus W protein subcellular localization in the nucleus or mitochondria. Journal of Virology 95(7):e02087-20.
14. Cheng JL, Zhao Y, Hu YX, Zhao J, Xue J, Zhang GZ*. 2021. The furin-S2' site in avian coronavirus plays a key role in central nervous system damage progression. Journal of Virology 95(11):e02447-20.
15. Qin YF, Tu KH, Teng QY, Feng DL, Zhao Y, Zhang GZ*. 2021. Identification of novel T-cell epitopes on infectious bronchitis virus N protein and development of a multi-epitope vaccine. Journal of Virology 95(17):e0066721.
16. Wu YF, Wang Y, Yang HM, Li Q, Gong X, Zhang GZ*, Zhu K*. 2021. Resident bacteria contribute to opportunistic infections of the respiratory tract. PLoS Pathogens 17(3):e1009436.
17. Gao L, Zhou J, Yang S, Wang L, Chen X, Yang Y, Li R, Pan Z, Zhao J, Li Z, Huang Q, Tang J, Hu L, Liu P, Zhang GZ*, Chen Y*, Ye L*. 2021. The dichotomous and incomplete adaptive immunity in COVID-19 patients with different disease severity. Signal Transduction and Targeted Therapy 6(1):113.
18. Shao L, Zhao J, Li LH, Huang XY, Yang HM, Cheng JL, Liu CQ, Zhang GZ*. 2020. Pathogenic characteristics of a QX-like infectious bronchitis virus strain SD in chickens exposed at different ages and protective efficacy of combining live homologous and heterologous vaccination. Veterinary Research 51:86.
19. Chen X, Pan Z, Yue S, Yu F, Zhang J, Yang Y, Li R, Liu B, Yang X, Gao L, Li Z, Lin Y, Huang Q, Xu L, Tang J, Hu L, Zhao J, Liu P, Zhang GZ*, Chen Y*, Deng K*, Ye L*. 2020. Disease severity dictates SARS-CoV-2-specific neutralizing antibody responses in COVID-19. Signal Transduction and Targeted Therapy 5(1):180.
20. Yang YL, Bu YW, Zhao J, Xue J, Xu G, Song Y, Zhao Y, Yang HM, Zhang GZ*. 2019. Appropriate amount of W protein of avian avulavirus 1 benefits viral replication and W shows strain-dependent subcellular localization. Virology 538:71-85.
21. Song Y, Pei Y, Yang YL, Xue J, Zhang GZ*. 2019. The Ntail region of nucleocapsid protein is associated with the pathogenicity of pigeon paramyxovirus type 1 in chickens. Journal General Virology 100(6):950-957.
22. Yan SH, Liu XY, Zhao J, Xu G, Zhao Y, Zhang GZ*. 2017. Analysis of antigenicity and pathogenicity reveals major differences among QX-like infectious bronchitis viruses and other serotypes. Veterinary Microbiology 203:167-173.
23. Yang HM, Zhao J, Xue J, Yang YL, Zhang GZ*. 2017. Antigenic variation of La Sota and genotype VII Newcastle disease virus (NDV) and their efficacy against challenge with velogenic NDV. Vaccine 35(1):27-32.
24. Zhao Y, Zhang H, Zhao J, Zhong Q, Jin JH, Zhang GZ*. 2016. Evolution of infectious bronchitis virus in China over the past two decades. Journal General Virology 97:1566-1574.
25.Feng JL, Hu YX, Ma ZJ, Yu Q, Zhao JX, Liu XD, Zhang GZ*. 2012. Virulent avian infectious bronchitis virus, People's Republic of China. Emerging Infectious Diseases 18(12):1994-2001.



