
姓名:吴文学
性别:男
职称:研究员
学位:博士
所在系:预防兽医系
导师类型:博导兼硕导
出生年月:1970.11
电子邮件:wuwenxue@cau.edu.cn
办公电话:010-62733048
个人简介
欧宝综合体育研究员,博导兼硕导,国家奶牛产业技术体系岗位科学家,主要从事牛羊传染病诊断技术与疫苗研发。主持国家“十四五”重点研发专项、国家自然科学基金等40余项,在PNAS、Analytical Chem等期刊发表论文80余篇,副主编《中国兽医诊疗图鉴》丛书、《畜禽疫病诊疗手册》丛书等7部,申请国家发明专利24项、授权国家发明专利 13 项,获国家新兽药证书4项(其中国家一类新兽药证书2项),培养硕士研究生41名、博士研究生26名。兼任全国动物防疫专家委员会委员、中国兽药典委员会委员、全国动物卫生标准化技术委员会委员、农业农村部兽药评审专家、中国兽医协会牛羊兽医分会副会长。
教育经历
1989.10-1994.07,北京农业大学,动物药学,本科;
1997.09-2002.07,欧宝综合app,预防兽医学,博士研究生。
工作经历
1994.07-1999.09,欧宝综合app,西校区科研处,研究实习员;
1994.10-1995.10,国家自然科学基金委生命科学部,借调;
1999.09-2004.05,欧宝综合app研究生院,助理研究员;
2003.01-2005.01,开封市郊区,副区长(挂职);
2004.05-2009.12,欧宝综合,副院长;
2005.01-2016.12,欧宝综合,副教授;
2013.10-2014.08,美国哈佛医ob欧宝电竞官网入口,访问学者;
2017.01-至今,欧宝综合,研究员(博导)。
研究领域
牛羊传染病新型诊断技术和疫苗研发
获奖及荣誉
农业农村部专项人才计划领军英才
教育部新世纪优秀人才
大北农科技一等奖(排名第1)
北京市科学技术进步二等奖(排名第1)
全国农牧渔业丰收一等奖
在研项目
1.草食家畜重要疫病新型诊断技术与产品研发项目 “十四五”国家重点研发计划 主持
2.现代农业产业技术体系-岗位专家 主持
3.长链非编码RNA 6up促进BHV-1在MDBK细胞中增殖的分子机制 国家自然科学基金-面上项目 主持
4.牛病毒性腹泻疫苗研发 横向项目 主持
代表性文章
近5年发表英文文章
1. Chenxuan Liu,?Xinyi Zhang,?Wenxue Wu*,?Tongxing Song.* Roles of Diverse Lipokines in Metabolic Homeostasis and Their Associations With Various Diseases.Comprehensive Physiology. Volume 15 , Issue 6 . 2025.
2. Yining Deng,Yunke Zhang,Tong Wu,?Chen Peng,?Wenxue Wu*.GalE's Role in Lipopolysaccharide O-Antigen Synthesis and Environmental Stress Resistance in STEC O5. Journal of basic microbiology. Volume 65 , Issue 11 . 2025.
3. Yining Deng,Yunke Zhang,Tong Wu,?Kang Niu,?Xiaoyu Jiao,?Wenge Ma,Chen Peng*,?Wenxue Wu*.Complement C3 deposition restricts the proliferation of internalized Staphylococcus aureus by promoting autophagy. Frontiers in Cellular and Infection Microbiology. Volume 14 , Issue . 2024.
4.Shijie Xie , Lianxin Cui , Zhiyi Liao , Junda Zhu , Shuning Ren , Kang Niu , Hua Li , Fei Jiang , Jiajun Wu , Jie Wang , Jian Wu , Baifen Song , Wenxue Wu *, Chen Peng *. Genomic analysis of lumpy skin disease virus asian variants and evaluation of its cellular tropism.NPJ Vaccines. 2024 Mar 21;9(1):65
5. Wang Jing,?Zhu Junda,?Ren Shuning,Zhang Zihui,Niu Kang,?Li Hua,?Wu Wenxue*,?Peng Chen*.The role of ferroptosis in virus infections. Frontiers in Microbiology. Volume 14 , Issue . 2023
6. Zhu Junda,Gao Xintao,Li Yijing,Zhang Zihui,Xie Shijie,Ren Shuning,Li Yarui,Li Hua,?Niu Kang,?Fu Shufang,?Deng Yining,?Li Yinü,?Moss Bernard,?Wu Wenxue*,?Peng Chen*.Human FAM111A inhibits vaccinia virus replication by degrading viral protein I3 and is antagonized by poxvirus host range factor SPI-1. Proceedings of the National Academy of Sciences of the United States of America. Volume 120 , Issue 35 . 2023
7. Song Baifen,Huang Yanmei,Ma Jinzhu,Yu Liquan,Yu Yongzhong,Peng Chen,Wu Wenxue*.Construction and Analysis of ceRNA Networks Reveal the Key Genes Associated with Bovine Herpesvirus Type 1 Infection. Infection and drug resistance. Volume 16 , Issue . 2023
8. Chen Shijun,Liu Mengyao,Zi Yunjiang,He Junyi,Wang Lin,Wu Yuanyuan,Hou Shicong*,Wu Wenxue*.Rational design of near-infrared ratiometric fluorescent probes for real-time tracking of β-galactosidase in vivo. Spectrochimica Acta Part A:Molecular and Biomolecular Spectroscopy. Volume 285 , Issue . 2023
9. Wang Pengpeng,Huang Shulin,Hao Chengwu,Wang Zhanhui,Zhao Haoran,Liu Mengyao,?Tian Xinrui,Ge Letu,Wu Wenxue*,Peng Chen*.Establishment of a Suspension MDBK Cell Line in Serum-Free Medium for Production of Bovine Alphaherpesvirus-1. Vaccines. Volume 9 , Issue 9 . 2021
10. Wang Zhanhui,Liu Mengyao,Zhao Haoran,Wang Pengpeng,Ma Wenge,Zhang Yunke,Wu Wenxue*,Peng Chen*Induction of Robust and Specific Humoral and Cellular Immune Responses by Bovine Viral Diarrhea Virus Virus-Like Particles (BVDV-VLPs) Engineered with Baculovirus Expression Vector System. Vaccines. Volume 9 , Issue 4 . 2021
11. Zhao Haoran,Zhang Yunke,Wang Zhanhui,Liu Mengyao,Wang Pengpeng,Wu Wenxue*,Peng Chen*.MBOVPG45_0375 Encodes an IgG-Binding Protein and MBOVPG45_0376 Encodes an IgG-Cleaving Protein in Mycoplasma bovis. Frontiers in Veterinary Science. Volume 8 , Issue . 2021



