姓名：王战辉
性别：男
职称：教授
职务：基础兽医学系主任/三亚研究院副院长（挂职）/兽医药理学与毒理学教研组主任
学位：博士
所在系：基础兽医系
导师类型：博导兼硕导
出生年月：1979.06
电子邮件：wangzhanhui@cau.edu.cn/Zhanhui.wang@foxmail.com
办公电话：010-62734565
个人简介
动物源食品安全检测技术北京市重点实验室副主任，兽医公共卫生安全全国重点实验室PI。入选 “高层次人才支持计划”领军人才（万人计划）、主持国家自然科学基金青B（原优青）。兼任中国畜牧兽医学会兽医药理与毒理学分会副秘书长、中华预防医学会食品卫生分会副主任委员、中国分析测试协会食品分析分会副主任委员等。主要围绕抗菌药物、霉菌毒素、非法添加物等小分子化合物开展半抗原理性设计、单克隆抗体精准创制、免疫分析检测原理与技术。主持“十四”国家重点研发计划项目、“十三”国家重点研发计划课题、国家自然科学基金和科技部国际科技合作专项等30余项。已在Adv Sci、Anal Chem、分析化学等发表研究论文150余篇，获授权国家发明专利20余项。（欢迎关注微信公众号：抗体故事）
教育经历
2002-2007 欧宝综合app 欧宝综合体育 博士
1998-2002 南京农业大学 欧宝综合体育 本科
工作经历
2016-至今 欧宝综合app 教授
2010-2015 欧宝综合app 副教授
2007-2009 欧宝综合app 讲师
获奖及荣誉
2024年 大北农科技奖一等奖
2023年 中华农业科技奖一等奖
2015年 国家技术发明奖二等奖
2013年 中华农业科技奖一等奖
2009年 全国优秀博士学位论文提名奖
2008年 北京市优秀博士学位论文奖
教学工作
本科生 《药物化学》
研究生《兽药残留快速检测技术》
研究生《硕士科技论文写作》
代表性文章
1. Leina Dou, Penghui Zhou, Fei Qi, Qing Li, Yuchen Bai, Liang Luo, Kai Wen, Wenbo Yu, Xuezhi Yu*, Jianzhong Shen*, Zhanhui Wang*. When AI meets AIE: machine learning in design function-oriented AIEgens for antibacterial ability. Chemical Engineering Journal, 2025, 524, 169426.
2. Liang Luo, Qing Li, Chen Xing, Chenglong Li, Yantong Pan, He Sun, Xuezhi Yu, Kai Wen, Jianzhong Shen, Zhanhui Wang*. Antibody-based therapy: An alternative for antimicrobial treatment in the post-antibiotic era. Microbiological Research, 2025, 290, 127974.
3. Peipei Li, Weilin Wu, Yuan Li, Zhihua Qin, Yingjie Zhang, Changfei Duan, Kai Wen, Wenbo Yu, Xuezhi Yu, Jianzhong Shen, Zhanhui Wang*. Antibody recognition profile-aided hapten design to modulate antibody generation with anticipated performance for immunoassay development. Analytical Chemistry, 2024, 96, 19869?19879.
4. Yingjie Zhang#, Jiafei Mi#, Weilin Wu, Jie Fei, Bochen Lv, Xuezhi Yu, Kai Wen, Jianzhong Shen*, Zhanhui Wang*. Investigation of antibody tolerance in methanol for analytical purposes: methanol effect patterns and molecular mechanisms. Advanced Science, 2024, 11, 2402050.
5. Yingjie Zhang#, Weilin Wu#, Qing Li, Penghui Zhou, Kai Wen, Jianzhong Shen, Zhanhui Wang*. The hapten rigidity improves antibody performances in immunoassay for rifamycins: immunovalidation and molecular mechanism. Journal of Hazardous Materials, 2024, 469, 133977.
6. Jie Fei#, Jiaqun Jiang#, Yuchen Bai, Weilin Wu, Xiangjun Zhao, Wenbo Yu, Kai Wen, , Xuezhi Yu, Jianzhong Shen, Zhanhui Wang*. A proof-of-concept sandwich enzyme-linked immunoassay development for small molecule. Analytical Chemistry, 2023, 95, 39, 14665–14674
7. Huijuan Yang, Natalia Vasylieva, Jiaxin Wang, Zhenfeng Li, Kai Wen, Wenbo Duan, Shuang Chen, Hui Meng, Xuezhi Yu, Jianzhong Shen, Bruce D. Hammock, Zhanhui Wang*. Precise isolation and structural origin of an ultra-specific nanobody against chemical compound. Journal of Hazardous Materials, 2023, 458, 131958.
8. Yingjie Zhang, Qing Li, Liang Luo, Changfei Duan, Jianzhong Shen, Zhanhui Wang*. Application of germline antibody features to vaccine development, antibody discovery and antibody optimization and disease diagnosis. Biotechnology Advances, 2023, 65, 108143.
9. Xiya Zhang#,Yuchen Bai#, Qianqian Tang, Minggang Liu, Li Nan, Kai Wen, Xuezhi Yu, Wenbo Yu, Jianzhong Shen, Zhanhui Wang*. Developemt of epitopephore-based rational hapten design strategy: A combination of theoretical evidence and experimental evaluation. Journal of Hazardous Materials, 2023, 445, 130615.
10. Yuchen Bai, Jie Fei, Weilin Wu, Leina Dou, Minggang Liu, Shibei Shao, Wenbo Yu, Kai Wen, Jianzhong Shen, Zhanhui Wang*. Minimum distance between two epitopes in sandwich immunoassays for small molecules. Analytical Chemistry, 2022, 94, 51, 17843–17852.
11. Yuan Li, Peipei Li, Yuebin Ke, Xuezhi Yu, Wenbo Yu, Kai Wen, Jianzhong Shen, Zhanhui Wang*. A rare monoclonal antibody discovery based on indirect competitive screening of single hapten-specific rabbit antibody secreting cell. Analyst, 2022, 147, 2942–2952
12. Yuan Li, Peipei Li, Yuebin Ke, Xuezhi Yu, Wenbo Yu, Kai Wen, Jianzhong Shen, Zhanhui Wang*. Monoclonal antibody discovery based on precise selection of single transgenic hybridomas with an on-cell-surface and antigen-specific anchor. ACS Applied Materials & Interfaces, 2022, 14, 17128?17141.
13. Yuchen Bai, Hui Jiang, Yingjie Zhang, Leina Dou, Minggang Liu, Wenbo Yu, Kai Wen, Jianzhong Shen, Yuebin Ke, Xuezhi Yu, Zhanhui Wang*. Hydrophobic moiety of capsaicinoids hapten enhancing antibody performance in immunoassay: evidences from computational chemistry and molecular recognition. Journal of Agricultural and Food Chemistry, 2021, 69, 9957–9967.
14. Chenglong Li, Huijuan Yang, Wenbo Yu, Xuezhi Yu, Kai Wen, Jianzhong Shen, Zhanhui Wang*. Engineering of organic solvent-tolerant antibody to sulfonamides by CDR grafting for analytical purposes. Analytical Chemistry, 2021, 93, 6008–6012.
15. Kai Wen#, Yuchen Bai#, Yujie Wei, Chenglong Li, Jianzhong Shen, Zhanhui Wang*. Influence of small molecular property on antibody response. Journal of Agricultural and Food Chemistry, 2020, 68, 10944–10950.
